Brazilian Journal of Biological Sciences (ISSN 2358-2731)



Home Archive v. 5, no. 11 (2018) Motta

 

Vol. 5, No. 11, p. 631-639 - Dec. 31, 2018

 

Post-Polio Syndrome



Monalisa Pereira Motta , Abrahão Augusto Juveniano Quadros , Mônica de Souza Brito Conti and Acary Souza Bulle Oliveira

Abstract
Among the late effects of poliomyelitis is the Post-Polio Syndrome (PPS), characterized by increased muscle strength loss, abnormal fatigue and pain after a period of stability of at least 15 years. The incidence and prevalence of PPS are unknown in the world and in Brazil, depending on the diagnostic criteria. The diagnosis of PPS is made by exclusion and there is no specific laboratory test, these only help to rule out other diseases. There is no curative treatment for PPS. Its etiology remains unknown. Strategies for their clinical management aim reducing muscle overusing and a balance active lifestyle is recommended to minimize the symptoms.


Keywords
Post-Poliomyelitis Syndrome; Neuromuscular disorders; Treatment; Management.

DOI
10.21472/bjbs.051102

Full text
PDF

References
Agre, J. C.; Rodriquez, A. A.; Franke, T. M. Strength, endurance, and work capacity after muscle strengthening exercise in postpolio subjects. Archives of Physical Medicine & Rehabilitation, v. 78, no. 7, p. 681-686, 1997. Available from: <https://www.archives-pmr.org/article/S0003-9993(97)90073-3/pdf<. Accessed on: Apr. 23, 2018.

Burger, H.; Marincek, C. The influence of Post-Polio Syndrome on independence and life satisfaction. Disability and Rehabilitation, v. 22, no. 7, p. 318-322, 2000.

Bruno, R. L.; Zimmerman, J. R.; Creange, S. J.; Lewis, T.; Molzen, T.; Frick, N. M. Bromocriptine in the treatment of post-polio fatigue: A pilot study with implications for the pathophysiology of fatigue. American Journal of Physical Medicine & Rehabilitation, v. 75, no. 5, p. 340-347, 1996.

Conde, M. T. R. P.; Oliveira, A. S. B.; Quadros, A. A. J.; Moreira, G. A.; Silva, H. C. A.; Pereira, R. D. B.; Silva, T. M.; Tufik, S.; Waldman, E. A. Post-Polio Syndrome: Epidemiologic and prognostic aspects in Brazil. Acta Neurologica Scandinavica, v. 120, p. 191-197, 2009. https://doi.org/10.1111/j.1600-0404.2008.01142.x

Chan, K. M.; Strohschein, F. J.; Rydz, D.; Allidina, A.; Shuaib, A.; Westbury, C. F. Randomized controlled trial of Modafinil for the treatment of fatigue in postpolio patients. Muscle Nerve, v. 33, p, 138-141, 2006. https://doi.org/10.1002/mus.20437

Dalakas, M. C. Intravenous immuneglobulin in autoimmune neuromuscular diseases. JAMA, v. 291, no. 19, p. 2367-2375, 2004. https://doi.org/10.1001/jama.291.19.2367

Dalakas, M. C. The Post-polio syndrome as an evolved clinical entity: Definition and clinical description. Annals of the New York Academy of Sciences, v. 753, p. 68-80, 1995. https://doi.org/10.1111/j.1749-6632.1995.tb27532.x

Dinsmore, S.; Dambrosia, J.; Dalakas, M. C. A double-blind, placebo-controlled trial of high-dose prednisone for the treatment of Post-Poliomyelitis Syndrome. Annals of the New York Academy of Sciences, v. 753, p. 303-313, 1995. https://doi.org/ 10.1111/j.1749-6632.1995.tb27556.x

Farbu, E. Update on current and emerging treatment options for Post-Polio Syndrome. Therapeutics and Clinical Risk Management, v. 6, p. 307-313, 2010. Available from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909497/pdf/tcrm-6-307.pdf>. Accessed on: Apr. 23, 2018.

Farbu, E.; Rekand, T.; Vik-Mo, E.; Lygren, H.; Gilhus, N. E.; Aarli, J. A. Post-Polio Syndrome patients treated with intravenous immunoglobulin: A double-blinded randomized controlled pilot study. European Journal of Neurology, v. 14, no. 1, p. 60-65, 2007. https://doi.org/10.1111/j.1468-1331.2006.01552.x

Gonzalez, H.; Khademi, M.; Andersson, M.; Piehl, F.; Wallström, E.; Borg, K.; Olsson, T. Prior poliomyelitis-IVIg treatment reduces proinflammatory cytokine production. Journal of Neuroimmunology, v. 150, n. 1/2, p. 139-144, 2004. https://doi.org/10.1016/j.jneuroim.2004.01.010

Gonzalez, H.; Sunnerhagen, K. S.; Sjoberg, I.; Kaponides, G.; Olsson, T.; Borg, K. Intravenous immunoglobulin for Post-Polio Syndrome: A randomised controlled trial. The Lancet, Neurology, v. 5, no. 6, p. 493-500, 2006. https://doi.org/10.1016/S1474-4422(06)70447-1

Halstead, L. S. Assessment and differential diagnosis for Post-Polio Syndrome. Orthopedics, v. 14, no. 11, p. 1209-1217, 1991.

Horemans, H. L. D.; Nollet, F.; Beelen, A.; Drost, G.; Stegeman, D. F.; Zwarts, M. J.; Bussmann, J. B. J.; de Visser, M.; Lankhorst, G. J. Pyridostigmine in Postpolio Syndrome: No decline in fatigue and limited functional improvement. Journal of Neurology, Neurosurgery & Psychiatry, v. 74, no. 12, p. 1655-1661, 2003. https://doi.org/10.1136/jnnp.74.12.1655

Howard, R. S. Poliomyelitis and the Postpolio Syndrome. BMJ, v. 330, p. 1-5, 2005. https://doi.org/10.1136/bmj.330.7503.1314

Jubelt, B.; Cashman, N. R. Neurological manifestations of the Post-Polio Syndrome. Critical Reviews in Neurobiology, v. 3, p. 199-220, 1987.

Khan, F. Rehabilitation for postpolio sequelae. Australian Family Physician, v. 33, no. 8, p. 621-624, 2004. Available from: <https://www.racgp.org.au/afpbackissues/2004/200408/20040803khan.pdf. Accessed on: Apr. 23, 2018.

Kaponides, G.; Gonzalez, H.; Olsson, T.; Borg, K. Effect of intravenous immunoglobulin in patients with Post-Polio Syndrome: An uncontrolled pilot study. Journal of Rehabilitation Medicine, v. 38, no. 2, p. 138-140, 2006. https://doi.org/10.1080/16501970500441625

Motta, M. P. Efeito terapêutico do uso da L-carnitina+piracetam na fadiga e na força muscular de pacientes com Síndrome Pós-Poliomielite (SPP): estudo clínico randomizado, duplo-cego, controlado com placebo. São Paulo: Universidade Federal de São Paulo, Escola Paulista de Medicina, 2017. (Master thesis).

Neves, M. A. O.; Mello, M. P.; Reis, J. P. B.; Rei, A. M.; Antonioli, R. S.; Nascimento, O. J. M.; Freitas, M. R. G. A Síndrome Pós-Polio e o processo de reabilitação motora: relato de caso. Revista Neurociências, v. 15, no. 4, p. 321-325, 2007. Available from: <http://www.revistaneurociencias.com.br/edicoes/2007/RN 15 04/Pages from RN 15 04-13.pdf>. Accessed on: Apr. 23, 2018.

Nollet, F.; Horemans, H. L. D.; Beelen, A.; Drost, G.; Zwarts, M. J.; de Visser, M.; Lankhorst, G. J. Pyridostigmine in Postpolio Syndrome: A randomized double-blinded trial. Neurology, v. 58, no. 2, p. 199-200, 2002.

Oliveira, A. S. B.; Maynard, F. M. Síndrome Pós-Poliomielite: aspectos neurológicos. Revista Neurociências, v. 10, no. 1, p. 31-34, 2002. Available from: <http://www.revistaneurociencias.com.br/edicoes/2002/RN 10 01/RN 10 01 5.pdf>. Accessed on: Apr. 23, 2018.

Oliveira, A. S. B.; Quadros, A. A. J. Síndrome Pós-Poliomielite: orientações para profissionais de saúde. São Paulo: SES/SP, 2008. (Versão para Internet). Available from: <http://www.saude.sp.gov.br/resources/ses/perfil/profissional-da-saude/homepage//sindrome_pos_poliomielite_.pdf>. Accessed on: Apr. 23, 2018.

On, A. Y.; Oncu, J.; Uludag, B.; Ertekin, C. Effects of Lamotrigine on the symptoms and life qualities of patients with Post-Polio Syndrome: A randomized, controlled study. Neuro Rehabilitation, v. 20, no. 4, p. 245-251, 2005.

Orsini, M.; Mello, M. P.; Antonioli, R. S.; Nascimento, O. J. M.; Freitas, M. R. G. A Síndrome Pós-Pólio e o processo de reabilitação motora: relato de caso. Revista Neurociências, v. 15, p. 321-325, 2008. Available from: <http://www.revistaneurociencias.com.br/edicoes/2007/RN 15 04/Pages from RN 15 04-13.pdf>. Accessed on: Apr. 23, 2018.

Peel, M. M.; Cooke, M.; Lewis, H. J.; Lea, R. A.; Moyle, W. A randomized controlled trial of coenzyme Q10 for fatigue in the late-onset sequelae of poliomyelitis. Complementary Therapies in Medicine, v. 23, no. 6, p. 789-793, 2015. https://doi.org/10.1016/j.ctim.2015.09.002

Quadros, A. A. J.; Conde, M. T. R. P.; Marin, L. F.; Silva, H. C. A.; Mesquita e Silva, T.; Paula, M. B. E.; Pereira, R. D. B.; Ramos, P. E.; Abe, G.; Oliveira, A. S. B. Frequency and clinical manifestations of Post-Poliomyelitis Syndrome in a Brazilian tertiary care center. Arquivos de Neuro-Psiquiatria, v. 70, no. 8, p. 571-573, 2012. https://doi.org/10.1590/S0004-282X2012000800002

Ramlow, J.; Alexander, M.; LaPorte, R.; Kaufmann, C.; Kuller, L. Epidemiology of the Post-Polio Syndrome. American Journal of Epidemiology, v. 136, no. 7, p. 769-786, 1992.

Rosa, L. N.; Cunha, M. C. B.; Franco, R. C. Qualidade de vida em indivíduos portadores da Síndrome Pós-Pólio. Arquivos Médicos do ABC, v. 31, no. 1, p. 18-22, 2006. Available from: <https://www.portalnepas.org.br/amabc/article/viewFile/230/226>. Accessed on: Apr. 23, 2018.

Rekand, T.; Korv, J.; Farbu, E.; Roose, M.; Gilhus, N. E.; Langeland, N.; Aarli, J. A.. Lifestyle and late effects after poliomyelitis. A risk factor study of two populations. Acta Neurologica Scandinavica, v. 109, no. 2, p. 120-125, 2004. https://doi.org/10.1034/j.1600-0404.2003.00186.x

Rowland, L. P.; Bach, J. R.; Borg, K.; Cashman, N. R.; Dalakas, M. C.; Dean, E.; Halstead, L. S.; Headley, J. L.; John, T. J.; Johnston, R. B.; Olkin, R.; Perlman, S. L.; Trojan, D. A.; Vickrey, B. G.; Wendling, W. W. March of Dimes International Conference on Post-Polio Syndrome: Identifying best practices in diagnosis & care. White Plains, NY: March of Dime, 2000. Available from: <https://www.polioplace.org/sites/default/files/files/MOD- Identifying.pdf>. Accessed on: Apr. 23, 2018.

Skough, K.; Krossén, C.; Heiwe, S.; Theorell, H.; Borg, K. Effects of resistance training in combination with coenzyme Q10 supplementation in patients with post-polio: A pilot study. Journal of Rehabilitation Medicine, v. 40, no. 9, p. 773-775, 2008. https://doi.org/10.2340/16501977-0245<

Stein, D. P.; Dambrosia, J. M.; Dalakas, M. C. A double-blind, placebo-controlled trial of amantadine for the treatment of fatigue in patients with the Post-Polio Syndrome. Annals of the New York Academy of Sciences, v. 753, no. 1, p. 296-302, 1995. https://doi.org/10.1111/j.1749-6632.1995.tb27555.x

Trojan, D. A.; Cashman, N. R. An open trial of pyridostigmine in Post-Poliomyelitis Syndrome. Canadian Journal of Neurological Sciences, v. 22, no. 3, p. 223-227, 1995. https://doi.org/10.1017/S0317167100039883

Trojan, D. A.; Cashman, N. R. Post-Poliomyelitis Syndrome. Muscle Nerve, v. 31, no. 1, p. 6-19, 2005. https://doi.org/10.1002/mus.20259

Trojan, D. A.; Cashman, N. R.; Shapiro, S.; Tansey, C. M.; Esdaile, J. M. Predictive factors for Post-Poliomyelitis Syndrome. Archives of Physical Medicine and Rehabilitation, v. 75, p. 770-777, 1994. Available from: <https://www.archives-pmr.org/article/0003-9993(94)90134-1/pdf. Accessed on: Apr. 23, 2018.

Trojan, D. A.; Collet, J.-P.; Shapiro, S.; Jubelt, B.; Miller, R. G.; Agre, J. C.; Munsat, T. L.; Hollander, D.; Tandan, R.; Granger, C.; Robinson, A.; Finch, L.; Ducruet, T.; Cashman, N. R. A multicenter, randomized, double-blinded trial of pyridostigmine in Postpolio Syndrome. Neurology, v. 53, no. 6, p. 1225-1233, 1999. https://doi.org/10.1212/WNL.53.6.122

Vasconcelos, O. M.; Prokhorenko, O. A.; Salajegheh, M. K.; Kelley, K. F.; Livornese, K.; Olsen, C. H.; Vo, A. H.; Dalakas, M. C.; Halstead, L. S.; Jabbari, B.; Campbell, W. W. Modafinil for treatment of fatigue in Post-Polio Syndrome: A randomized controlled trial. Neurology, v. 68, no. 20, p. 1680-1686, 2007. https://doi.org/10.1212/01.wnl.0000261912.53959.b